China's oyster-inspired 'bone glue' bonds fractures in minutes

Chinese researchers have developed a novel medical adhesive called “Bone-02,” inspired by the natural adhesive oysters use to attach to underwater surfaces. This bio-glue can bond fractured bones within 2–3 minutes, even in moist, blood-rich environments where traditional adhesives fail. Unlike conventional methods requiring metal plates and screws, Bone-02 can be injected directly into the fracture site, providing strong fixation with bonding strength exceeding 400 pounds and notable shear and compressive strengths. Additionally, the glue is biodegradable, eliminating the need for implant removal surgeries, and early tests indicate it reduces infection risks compared to metal hardware. The innovation promises to revolutionize orthopedic surgery by enabling faster, less invasive procedures with smaller incisions and potentially eliminating permanent implants. Its strong fixation improves bone alignment and healing, lowering complications and healthcare costs. If ongoing clinical trials confirm these benefits, Bone-02 could transform treatment for complex fractures, allowing bones to be effectively “glued” back together and heal naturally rather than being reconstructed with metal hardware