New lab-built neuron achieves brain-like function at only 0.1 volts

Researchers at the University of Massachusetts Amherst have developed an artificial neuron that closely mimics the electrical function of biological neurons while operating at an ultra-low voltage of just 0.1 volts—comparable to the voltage in human neurons. This breakthrough builds on prior work using protein nanowires derived from the electricity-generating bacterium Geobacter sulfurreducens. Unlike previous artificial neurons that required significantly higher voltages and power, this new design drastically reduces energy consumption, potentially enabling more efficient bio-inspired computing systems and seamless integration with living cells. The low-voltage artificial neurons could revolutionize wearable electronics and medical devices by eliminating the need for signal amplification, which currently increases power use and circuit complexity. This advancement opens possibilities for electronics that directly interface with the human body, enhancing efficiency and functionality. The research team envisions applications ranging from ultra-efficient computers modeled on brain principles to novel biomedical devices. Their findings, supported by multiple U.S. agencies, were published in Nature Communications, marking a significant step toward