Self-powered microneedle patch monitors biomarkers without blood

Researchers have developed a self-powered microneedle patch that enables painless, blood-free collection of health biomarker samples from dermal interstitial fluid (ISF) just below the skin’s surface. Unlike traditional blood tests, which require needles and complex processing to isolate relevant fluids, this patch uses microneedles that swell upon contact with ISF, drawing the fluid into a paper layer where it is stored. The patch can collect and store biomarkers for up to 24 hours, allowing for easier and faster health monitoring without the need for batteries or external devices. In proof-of-concept tests on synthetic skin, the patch successfully measured cortisol, a stress biomarker, within 15 minutes, demonstrating potential for frequent, noninvasive monitoring of various health indicators. Made from inexpensive materials, the patch eliminates the need for phlebotomists and blood collection supplies, potentially transforming home and clinical diagnostics. The research team is advancing human trials and developing electronic readers to analyze the collected samples, seeking industry