TX-GAIN: MIT supercomputer to power generative AI breakthroughs

Source: interestingengineering
Author: @IntEngineering
Published: 10/6/2025
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Read original articleMIT’s Lincoln Laboratory Supercomputing Center (LLSC) has unveiled TX-GAIN, the most powerful AI supercomputer at a U.S. university, designed primarily to advance generative AI and accelerate scientific research across diverse fields. With a peak performance of 2 exaflops, TX-GAIN ranks on the TOP500 list and stands as the leading AI system in the Northeast. Unlike traditional AI focused on classification tasks, TX-GAIN excels in generating new outputs and supports applications such as radar signature evaluation, supplementing weather data, anomaly detection in network traffic, and exploring chemical interactions for drug and material design.
TX-GAIN’s computational power enables modeling of significantly larger and more complex protein interactions, marking a breakthrough for biological defense research. It also fosters collaboration, notably with the Department of Air Force-MIT AI Accelerator, to prototype and scale AI technologies for military applications. Housed in an energy-efficient data center in Holyoke, Massachusetts, the LLSC supports thousands of researchers working on
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